منابع مشابه
Lithium-induced Nephropathy
1. Department of Radiology, Antwerp University Hospital, University of Antwerp, Edegem, Belgium Background: A 59-year-old man was referred for CT scan of the abdomen after repair of an eventrated appendectomy wound. The man had a known history of bipolar affective disorder, for which he had been on lithium therapy for many years. As an incidental finding, CT scan showed numerous small hypodense...
متن کاملMRI findings in chronic lithium nephropathy: a case report.
Patients on long term lithium therapy for affective disorders may develop renal toxicity. It may manifest as nephrogenic diabetes insipidus with renal biopsy showing interstitial fibrosis, sclerotic glomeruli and cyst formation. Magnetic resonance imaging demonstrates the presence of microcysts in patients on long-term lithium therapy, suggesting a possible cause for their nephrotoxicity. We de...
متن کاملInhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy.
TGF-β1 upregulates microRNA-192 (miR-192) in cultured glomerular mesangial cells and in glomeruli from diabetic mice. miR-192 not only increases collagen expression by targeting the E-box repressors Zeb1/2 but also modulates other renal miRNAs, suggesting that it may be a therapeutic target for diabetic nephropathy. We evaluated the efficacy of a locked nucleic acid (LNA)-modified inhibitor of ...
متن کاملThe pathology of lithium induced nephropathy: a case report and review, with emphasis on the demonstration of mast cells.
Lithium is a psychotropic agent which is widely employed in the psychiatric practice throughout the world. The therapeutic index of lithium is low and an acute intoxication may appear, which may lead to death or a permanent disability. A frequent side effect of lithium is renal toxicity. The collecting tubules have been identified as the site of action of lithium, due to the down regulation of ...
متن کاملVitamin C-induced oxalate nephropathy: a case report
Therapeutic benefits of vitamin C is an area of active research and large doses have been suggested by many studies for treatment of various conditions. We are describing a case of oxalate nephropathy leading to end stage kidney disease, which occurred secondary to mega-dose of oral vitamin C. Increasing the awareness between medical personnel as well as patients will clearly decrease the incid...
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ژورنال
عنوان ژورنال: Radiology
سال: 2013
ISSN: 0033-8419,1527-1315
DOI: 10.1148/radiol.13111801